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PMID: 15684699

Species difference of esterase expression and hydrolase activity in plasma

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In brief, when TrkB and p75 NTR co-express in the same cells, p75 NTR enhances neurotrophin binding to TrkB, augmenting both ligand affinity and selectivity, hence, reinforcing the TrkB-mediated trophic response via up-regulation of PI3K/Akt and/or IRAK/NF-B signaling 3
Stedehouder J, Couey JJ, Brizee D, Hosseini B, Slotman JA, Dirven CMF, et al
