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A two-step progression from simple steatosis to steatohepatitis and fibrosis has been proposed 13 , and suggests that after fat accumulation in the liver due to insulin resistance, lipids are peroxidized with cytokines and Fas ligand induced by excessive ROS

This study reinforced the concept that massive doses of B12whether delivered via injection, nasal drop, or highly concentrated sublingual liquidare required to force the vitamin across the blood-brain barrier via passive diffusion to relieve localized central nervous system deficiencies

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However, it's important to approach supplementation thoughtfully, considering dietary, lifestyle, and medical factors

Always consult a healthcare provider for personalized advice