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Under normal homeostatic conditions, CD38 is expressed at low levels, whereas rising expression of CD38 with aging plays a vital role in age-associated NAD + reduction

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Researchers frequently employ *in vitro* models, such as primary cell cultures or established cell lines, where oxidative insults are induced using agents like hydrogen peroxide, menadione, or paraquat

These rats were obtained from the experimental animal house at Nahda University, Beni Suef

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