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However, the effects of PCSK9 in regulating EC metabolism and atherosclerosis still need to be investigated

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Lipid peroxidation leads to the generation of harmful byproducts, such as 4-hydroxy-2-nonenal (4-HNE) and malondialdehyde (MDA) [47, 49, 50]

However, the performance of Tbr1 +/ mice provisioned with the 1/4 cocktail supplement was comparable to that of their WT littermates (Fig 8E)

The peptide also reduces oxidative stress and inflammation by regulating antioxidant gene expression, protecting skin from aging triggers

The GSH/GSSG ratio is widely recognized as a sensitive indicator of oxidative stress (Kern & Jones, 2006
