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Description
At the genetic epidemiology level, Mendelian randomization-based analyses provide support for causal relationship hypotheses, though evidence strength remains preliminary (155)

Glucose-1-phosphate is an allosteric activator of G6PDH resulting in an enhanced level of NADPH production in response to oxidative stress
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10.3389/fphar.2022.1014933 Front Pharmacol

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MTHFR contributes to those conditions as well
