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These regulatory mechanisms encompass gene expression, protein modification, and intercellular communication, with TAMs precisely orchestrating tumor cell growth, development, invasion, and metastasis through diverse signaling pathways (43, 44)

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In addition, controlling epigenetic modifications suggests the potential regulation of phenotypic expression that the fruit ripening and tuberization in tomatoes and potatoes entail, hence, creating more possibilities in breeding strategies (Zhang et al., 2024b)

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