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[Molecular Pharmacology, 2015, vol

As of 2026 the compound rests on a small number of pilot human studies, with no completed controlled efficacy trial and no active large scale recruitment

in contrast, in the malignant ascites of ovarian cancer, abundant TAMs can be found, which are primarily M2-like with pro-tumor capacity (Gupta et al., 2018)

Although estrogen levels can reach the pregnancy-like concentrations during ovulation in healthy individuals, the oligo/anovulation characteristic of PCOS leads to a deficiency in high estrogen levels, which may predispose individuals to excessive inflammation

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