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The observed increase in interferon synthesis and improved markers of insulin sensitivity suggest systemic benefits beyond localized cellular effects [77]

Pre-fractionation of peptides was mostly beneficial for identifying adducted peptides

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Assuming low concentrations in the vacuole and apoplast, this would give a concentration of around 2 mM in other compartments, in reasonable agreement with reported values in spinach chloroplasts and the cytosol/cytoplasm of Arabidopsis cells (Foyer and Halliwell, 1976