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Upon oxidative stress, sudden MPT causes massive ion influx that dissipates mitochondrial membrane potential and shuts down OXPHOS, ATP production and ROS overgeneration

CCK-8 method Cells were seeded into 96-well plates at a density of 2,500 cells per well

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Cantin, A.M., North, S.L., Hubbard, R.C

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doi: 10.1006/abio.1999.4209