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Downstream events of PI3KC3-C1 activity result in the formation of LC3-PE, an autophagic cargo tether, formed by the conjugation of LC3-I (microtubule-associated protein 1A/1B-light chain 3) protein and the PE (phosphatidylethanolamine) lipid [40]

Influence of extracellular zinc on M1 microglial activation

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Watch and Wait in Rectal Cancer Patients with Clinical Complete Response to Neoadjuvant Therapy

At the protein level, FOXO4-DRI apparently reduced markers tied to myofibroblasts and matrix deposition, including -SMA and Col1a1

Previous studies have revealed that long-term radiation exposure led to increased amyloid (A) deposition in the hippocampus and cognitive impairment [83,84]