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doi: 10.1186/1423-0127-17-S1-S45

Heavy drinking can lead to throat and mouth cancers
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The PERK-ATF4-CHOP pathway is a central signaling cascade activated in response to ER stress, serving as the cells primary reaction to dysfunction and playing a crucial role in cellular survival
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Impaired insulin sensitivity is a hallmark of insulin resistance, a precursor to type 2 diabetes
