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Description
Alternative platelet activation pathways and their role in neurodegenerative diseases

In contrast, Nrf2 binds to a cis -acting enhancer with a core nucleotide sequence of 5-RTGACNNNGC-3, that is also known as the antioxidant response element (ARE), or the electrophile response element (EpRE), to control the basal and inducible expression of over 1000 genes that can be clustered into several groups with distinct functions, including antioxidative defense, detoxification, inflammatory responses, transcription factors, proteasomal and autophagic degradation, and metabolism ( Structural features of vertebrate Nrf2 have been revised and updated in detail (Silva-Islas and Maldonado, 2018

By delivering the bodys primary antioxidant directly through the nose, this method aims to support brain chemistry and cellular defenses more efficiently than standard oral supplements

Acknowledgements We thank the BATS team for quality controlling cruise CTD data
10.1182/blood-2008-04-149385 10 ArgyriouA

doi: 10.1186/s12903-024-04936-w 130 MeyersAKZhuX
