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With respect to cognitive function, choline is needed for myelination of nerves and is a precursor for acetylcholine an important neurotransmitter involved in muscle action, memory, and other functions

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IGF-1 signaling disruption determines macrophage activation into the pro-inflammatory M1 phenotype and reduces lipid efflux, promoting lipid accumulation in macrophages (119, 147)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 87.Ohlsson C

When evaluating the overall accuracy of the MDM System, it should be noted that some, but not all, of the participants overlapped between the quantitative and semiquantitative analyses