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Summarizing the data on the mechanisms of necroptosis, it can be noticed that this kind of programmed cell death requires mitochondrial and cytosolic ROS [216, 217]
Additionally, ATP-binding cassette transporters, such as ABCA1 and ABCG1, regulate cholesterol and lipid efflux from endothelial cells, thereby modulating BBB permeability (Rohrer et al., 2009)
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Analysis of N- and K-ras mutations in the distinctive tumor progression phases of melanoma
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