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TMAO stands out as a potential biomarker in CKD, which need to validate in the large-scale study and in different populations

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It is a form of carnitine that is naturally produced in the body and is involved in energy production and metabolism

While we emphasizes on improving clinical diagnosis using microbial signatures, we acknowledge that future validation studies should also include head-to-head comparisons with established non-invasive tests such as FIB-4 and elastography to determine the relative diagnostic performance and clinical utility of microbiome-based approaches

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EAZA Annual Conference Sept 2022