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The following data were evaluated for eligibility in each study: first authors surname, publication year, country of study, study design, sample size, follow-up duration, characteristics of participants, disease targeted, and major results
2729 Currently, three major signaling proteins including c-Jun N-terminal kinase (JNK), Nrf2, and p53 have been found to be involved in mitochondrial oxidative stress
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This makes them more susceptible to toxins, which can lead to liver congestion
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10.1016/S0165-3806(97)00108-9 Dev
