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1 Introduction Liver diseases cause over 2 million deaths annually, accounting for 4% of all global deaths (1 in every 25 deaths) ( Approximately two-thirds of all liver-related deaths occur in men ( HCC develops through a complex, multi-stage biological process

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Observational studies showed that short sleep duration and poor sleep quality were associated with increased risk of MASLD in middle-aged 111 and younger people 112

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Ramadori P, Kam S, Heikenwalder M

The nervous system of dauer larvae exhibits a handful of features that emphasize this stages adaptation for stress resistance and energy conservation