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Circulation 147, 650666
doi: 10.1002/mrm.10443
Risk factors include a family history of IBD, smoking, and certain genetic mutations, notably in the NOD2/CARD15 gene, which are associated with ileal involvement and a stricturing phenotype Diagnosis is established through a combination of clinical evaluation, endoscopic examination with biopsy, imaging studies, and laboratory tests
Fibroblast growth factor receptors as therapeutic targets in human melanoma: synergism with BRAF inhibition
