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[DOI] [PMC free article] [PubMed] [Google Scholar] 53.Hopkins, E
NNMT is over-expressed in a large proportion in renal cell cancers
NNMT is overexpressed in adipose tissue and various cancer cell lines, and its inhibition has been studied as a strategy to increase intracellular NAD+ levels, enhance one-carbon metabolism, and reduce adipogenesis in preclinical models
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