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When these nutrients are deficient or the metabolic pathways become less efficient, homocysteine accumulates in the bloodstream and serves as a useful marker of impaired methylation and disrupted one carbon metabolism

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Chapter 21, Water soluble vitamins, cobalamin

B12 helps with red blood cell formation and anaemia prevention

51 JandricI.VrcicH.Jandric BalenM.KolencD.BrcicL.RadicB.et al (2013)

Dark spots form when melanin production becomes uneven or excessive in certain areas (a process called hyperpigmentation)