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4 Discussion The enteric nervous system (ENS), often referred to as the second brain, not only autonomously regulates local intestinal physiological functions but also engages in bidirectional communication with the central nervous system (CNS) via the gutbrain axis

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In addition to the final rule, which adds six ingredients to the positive list and excludes four others, compounders must also be aware of the interim guidance for other ingredients that have been nominated for the 503A Bulk Substances List

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Cleveland Clinic.

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