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[DOI] [PMC free article] [PubMed] [Google Scholar] 147

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Neurons are exquisitely sensitive to oxidative stress and require high levels of NADPH to generate antioxidant defense systems regulated by GSH and Trx

Glutathione levels are affected by both internal and external factors

In preclinical models, these mechanisms translate into broad potential applications, including wound healing, muscle and tendon repair, gastrointestinal ulcer protection, and recovery from NSAID-induced damage

(E) Persistent colovesical fistula and BPC 157 therapy effect