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oleifera fruit extract is a safe and potential anticancer drug

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Protonate3D: assignment of ionization states and hydrogen coordinates to macromolecular structures

It can also disrupt TJ proteins, leading to increased permeability of the BBB and upregulation of the target gene VEGF , thereby exacerbating vascular leakage

Shaw P, Chattopadhyay A

Other studies suggest initial dopamine agonist therapy delivers results similar to those seen in L-DOPA plus COMT inhibitor therapy