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Diabetes and alpha lipoic Acid

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Additionally, CBP inhibited hydrogen peroxide (HO)-induced apoptosis in SRA01/04 lens epithelial cells by upregulating the expression of the anti-apoptotic protein Bcl-2 and downregulating the expression of pro-apoptotic proteins Caspase-3 and Bax

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Main limitation: selectivity figures (such as an in-vitro ~11.7-fold preference for senescent cells) come from cell models, not humans