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This study aims to verify the effects of supplementation with selenium, iron, and vitamin E, on the incidence of diarrhea, oxidative metabolism, blood metabolites, hematological parameters, and performance of calves under immunological challenge with Anaplasma marginale in the suckling phase

10.1016/j.ejphar.2015.10.023 64 HeM.MinJ.-W.KongW.-L.HeX.-H.LiJ.-X.PengB.-W

doi: 10.1007/s10787-021-00889-6 [DOI] [PMC free article] [PubMed] [Google Scholar] 174

The pivotal NEJM trial reported that the percentage of patients experiencing symptoms of growth hormone excess including joint pain, peripheral edema, and muscle aches was lower than seen in earlier large trials of growth hormone itself in HIV-infected patients

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Whether this is an alternative mechanism of action for this drug is unknown