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In order to generate a large sample population and exclude any possible bias, like the Hawthorne study shows, this retrospective study design was chosen to resemble daily clinical practice routines 51

Neurology 64:20402045

doi: 10.1155/2014/390601 75 VerschuurC

Vouldoukis I, Conti M, Krauss P et al

Glycocalyx is now a universal term that describes the sugary coat of cells and encompasses a variety of names that define the polysaccharide coat specific to a particular cell type, e.g., cell wall, mucous coating, zona pellucida, cuticle, red-cell antigen, etc

SURMOUNT-1 demonstrated this clearly when comparing tirzepatide results to historical semaglutide data