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(Biochemical Pharmacology 2019) established that NNMT protein expression is elevated ~3-fold in aged skeletal muscle compared to young muscle in preclinical models, and that 5-amino-1MQ treatment was associated with altered muscle stem cell (muSC) proliferation and differentiation endpoints in C2C12 myoblast research systems

Palmer A

Description & Pharmacodynamics 5-Amino-1MQ is a selective inhibitor of NNMT, an enzyme involved in regulating cellular methylation balance and energy metabolism

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