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We also provide evidence that the link between promotion of mitochondrial biogenesis and reduced production of ROS through the up-regulation of PGC-1 might be a possible underlying mechanism for their protective effects

Ignoring the problem can lead to long-term health effects and lower quality of life
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J Clin Med (2022) 11(15):23072319

54 Its major apolipoprotein, Apo AI, is synthesised by the liver and to a lesser extent the small intestine