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Chronic psycho-socioeconomic stress, early life adversity, depression, post-traumatic stress disorder, obesity, or prolonged use of sGCs are conditions usually associated with dysregulation of the HPA axis [4]

Sleep duration and the risk of breast cancer: the Ohsaki Cohort Study
Feb;26(2):969

Similar findings have been implicated in the pathogenesis of bipolar disorder, including the involvement of elevated free radicals such as NO, as well as lipid peroxidation and altered antioxidant levels (157, 162)

Zhang B, Shen J, Zhong Z, Zhang L

Journal of Molecular Endocrinology 52(3): R47R63 (2014)
