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TRIUMPH-4 was the first to report positive results in December 2025

Those tissue injuries lead fibroblasts to produce extensive ECM to increase interstitial stresses [84]

Despite its minimal presence in other foods like grains, vegetables, and meat, its biosynthesis has only been observed in specific fungi [2]

Conclusions The inflammatory process seen in MS is due to an excess production of proinflammatory cytokines, which leads to increased secretion of ROS

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