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References 1.Dolati S, Sadreddini S, Rostamzadeh D, Ahmadi M, Jadidi-Niaragh F, Yousefi M

Consequently, newly generated dialdehyde group in oHA was able to be covalently cross-linked with amino groups in CMCTS via a Schiff base reaction [32, 33]

Advanced Glycation End-Products (AGEs): Formation, Chemistry, Classification, Receptors, and Diseases Related to AGEs

The downsides are real

6).37 The remaining 15% of low-grade gliomas also occur more frequently in the first 10 years of life, and can appear in any part of the brain

Practically yes
