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Combination of Erastin or SOR with low-dose CDDP can effectively inhibit the growth of CDDP-resistant NSCLC cells (N5CP) in vivo, and promote ferroptosis by inducing the accumulation of intracellular lipid peroxides [198]

as to mitochondrial GSTs and MAPEG, we refer the reader to other excellent reviews 7,8

In which of the following tissues would pentose phosphate pathway be expected to be the least active

*Correspondence: Chun Guang Li, [email protected] These authors have contributed equally to this work This article was submitted to Ethnopharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Given the earlier evidence of combined AMN and DNA condensation activity by Cu 3 -TC-Py, we hypothesised this cytological profile may arise due to near-total degradation of the genetic material