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Deteriorated antioxidant defenses and diminished activity of crucial enzymes engaged in lipid peroxide detoxification have been witnessed in AD, further corroborating the participation of ferroptosis in neuronal expiration [502, 517]

In 2003, Dean et al

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If the local pH environment is unsuitable, the peptide may show cloudiness, floating particles, clumping, gel-like behaviour, aggregation, or precipitation