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Males, conversely, showed only 239 significant DEGs, with 159 being upregulated, and 80 being downregulated

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270 Dickkopf-2 (DKK2), a negative regulator of Wnt/-catenin, is involved in the activation of macrophages during atherosclerosis

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Indeed, studies using a primary cerebral cortical neuron culture have revealed that, in response to G activation, D2-like receptors enhance IP3R-1 gene transcription by promoting the binding of AP-1 and NFATc4 to the IP3R-1 promoter region [52]

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