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Actas Dermosifiliogr (English Edition) 107(6):e39e45

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This study was to investigate whether the transient receptor potential vanilloid channel type 1 (TRPV1) activation induces hyperosmotic effects on proinflammatory cytokine and chemoattractant release, and further explore the effects of osmoprotectants (L-carnitine, erythritol and betaine) on pro-inflammatory mediators by evaluating the ability to suppress their production in primary human corneal epithelial cells (HCECs) exposed to hyperosmotic stress

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