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Treated animals exhibited reduced interest in their surroundings and repetitive self-injurious behavior 4 weeks after the termination of treatment, possibly due to the downregulation of the OXTR over time [88]

On the other hand, ferroptosis can directly impair the antitumor immune response by negatively affecting key immune cells, including natural killer (NK) cells, B cells, cytotoxic T cells, and antigen-presenting cells (APCs), which are critical components of antitumor immune defense

Additionally, SAG lowered the protein stability of GPX4 through E3 ligase STUB1-mediated ubiquitination and degradation of endogenous GPX4

Hydrogen sulfide accelerates cell cycle progression in oral squamous cell carcinoma cell lines

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The intervention group, which participated in a 4-week program of supervised physical exercise, including aerobics, strength training, and Nordic walking, showed significant improvements in the 6-min walking test (6MWT), standing up and walking test, and spirometry values such as FEV1 and FEV1/FVC