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Exercise-mediated browning of white adipose tissue: its significance, mechanism and effectiveness

In normal cells, most endogenous fatty acids are synthesized from the citric acid in the TCA cycle

A great deal of GH biology is thought to depend on the pattern of exposure, not just the total amount: pulsatile GH and continuous GH can produce different downstream gene-expression and metabolic effects in target tissues, which is one reason natural secretion is so tightly pulsatile in the first place