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doi: 10.1016/j.bbadis.2009.08.013

Abstract Alopecia areata (AA) is an inflammatory autoimmune disease characterized by non-scarring hair loss on the scalp or any other part of the hair-bearing skin

Thus, elevated levels or activity of these mediators might provide an explanation for CD38 upregulation noted in SSc skin biopsies 24

Multiple studies have linked low vitamin B12 levels with impaired cognitive functioning and depressive symptoms, which can result from insufficient neurotransmitter production and damaged myelin sheaths

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Piperine was known for the enhancement of bioavailability of the drug components from the ancient times