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However, platelets from this patient clearly expressed very low NBEAL2 levels (Figure 3A,B)

The pathophysiology of migraine is unclear but seems to include a genetic component and a neurovascular component

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General anesthesia is not required

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Mechanistically, the overexpression of GPX4 protects cells from apoptosis by detoxifying the oxidative damage of membrane lipids, inhibiting mitochondrial release of CYCS, and inactivating caspase 3 [87]