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Dopamine agonists provide a symptomatic benefit that is comparable to that of levodopa/carbidopa in early disease, but these agents lack sufficient efficacy to control signs and symptoms by themselves in more advanced diseases (Hauser & Benbadis, 2020)

The only urine validity tests that might flag a sample are those looking for dilution (low creatinine and specific gravity) or adulteration (unusual pH or oxidizing agents)

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