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Description
NO donors such as sodium nitroprusside and S -nitrosoglutathione promote S -nitrosylation at the Cys183 residue of extracellular signal-regulated kinase 1/2 (ERK1/2), which leads to inducing apoptosis in U251 glioma cells (70)

The column was washed with acetonitrile for 10 min followed by a linear gradient back to the initial mixture of 30% acetonitrile with the flow rate 1 ml/min

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Dixon SJ, Lemberg KM, Lamprecht MR et al (2012) Ferroptosis: an iron-dependent form of nonapoptotic cell death

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This creates a slower, more sustained rise in circulating glutathione compared to an IV push, without requiring an infusion appointment
