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Biomarker monitoring, including fasting insulin, HOMA-IR, HbA1c, and body composition, is essential for assessing clinical response during a 12-week MOTS-c protocol

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Effects of exposure to DEHP during pregnancy on the expression levels of IGF-1, NKB, and GnRH in the hypothalamus of female offspring rats The ELISA results revealed that DEHP exposure upregulated the expression of IGF-1 in the hypothalamus of female offspring, demonstrating a clear dose-response relationship, with higher doses correlating with increased levels of IGF-1 expression (Fig