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doi: 10.1007/s12011-012-9491-9

This reaction is carried out by lactate dehydrogenase, (LDH)

Because it originates in gastric juice, its natural target tissues are the stomach, small intestine, and colon

Del Duca E, Morelli P, Bennardo L, Di Raimondo C, Nistic SP

Takenaka K, Fujii T, Kawamoto A, Suzuki K, Shimizu H, Maeyashiki C, Yamaji O, Motobayashi M, Igarashi A, Hanazawa R, Hibiya S

This increase in extracellular 5-HT in the intestinal mucosa activates the 5-HT receptors (such as 5-HT3) of myenteric neurons, smooth muscle cells, and epithelial cells, which causes increased intestinal secretion and motility to aid in pathogen clearance [272, 276, 277]