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Studies suggest 10-20 times higher tissue concentrations compared to topical application of equivalent amounts

The primary subjects were spontaneously obese rhesus macaques ( Macaca mulatta ), considered one of the most relevant primate models for human obesity

Each pen comes preloaded, which allows you to administer controlled doses with ease

These results collectively indicate that Sirt1 is indispensable for NNMT-mediated regulation of glucose metabolism, and both NNMT and MNAM have the ability to upregulate Sirt1 expression

Campagna, R., et al

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