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This review aims to systematically expound on these dual physiological and pathological roles, arguing that such disease-specific metabolic alterations not only provide biomarkers but, more importantly, unveil targetable vulnerabilities, thereby positioning amino acid metabolism as a strategic frontier for developing novel therapeutics across liver diseases

Novel selective small molecule agonists for peroxisome proliferator-activated receptor delta (PPARdelta)synthesis and biological activity

PAR polymers released during PARthanatos act as DAMPs, activating microglial and pyroptosis in neighboring neurons [82]

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Biochemistry Journal

This study reported beneficial effects on health, with moderate-intensity exercises, including dance, being among the main activities that improved motor symptoms [134]