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Glutamine is an essential fuel for rapidly dividing cells, such as enterocytes, fibroblasts, and leukocytes because it is a precursor of peptides, proteins, nicotinamide adenine dinucleotide phosphate (NADPH), antioxidants, purines, and pyrimidines ( When glutamine concentration lowers under one of the stressful conditions mentioned above, cells, such as lymphocytes, macrophages, and neutrophils, have their function and performance impaired due to the lack of their primary source of fuel

Acetylation and methylation levels of H3K9 were found to be increased and decreased, respectively, when treated with EGCG

Amsterdam: Elsevier (2016)

A further consideration is that some trace amines are metabolised by monoamine oxidase (MAO) enzymes, a catabolism process that also produces hydrogen peroxide as byproduct (Bortolato et al

So there's even a couple of different classes regulatory-wise

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