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In fact, some people do this when they need extra B12 but still want the broader benefits of the other B vitamins

Nicotinamide (niacinamide) does not cause flushing and has fewer side effects, with nausea and liver toxicity reported only at very high intakes ~3 g/day)

3 Another study showed that vitamin B12 levels were significantly lower after 4 months of treatment with isotretinoin for acne vulgaris

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