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[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Walter P., Schaffhauser A.O., Zurbriggen E., Siebrecht S., Fuhrmann M., Krhenbhl S., Lster H., Maggini S., Bnziger K.R., Kraemer W.J., et al

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Inclusion of a triantennary N -acetylgalactosamine (GalNAc 3 ) complex conjugated to the oligonucleotide or siRNA, enhances liver specificity resulting in greater potency at lower doses as well as reduced systemic toxicity (Table 2) [68]
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