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Research has shown that excessive iron accumulation occurs in the synovium in haemophilic arthropathy, resulting in synovitis (150, 166)

doi: 10.1016/S0002-9440(10)61135-2

The histidine residue serves as the primary copper-binding site, while the lysine residue contributes to cellular uptake through electrostatic interactions with negatively charged cell membranes

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MK-677 is prohibited under S2.2.4 as a growth hormone secretagogue mimetic