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[DOI] [PubMed] [Google Scholar] [163].Niederreither K, Subbarayan V, Dolle P, Chambon P
A number of studies have also assessed phenol levels in patients with different diseases, including colon cancer, familial polyposis, and Crohn's disease.54 Patients with diverticular disease or polyposis with ileorectal anastamosis appeared to have elevated urinary phenol levels (about 2-fold) relative to normal individuals
Nevertheless, since the role of ROS in disease is complex, treatments using direct antioxidants run the risk of oversimplification
Encouragingly, little acute toxicity has been observed in mouse models with ferroptosis inducing agents (59)
Heyneke et al
